Prostate-specific antigen (PSA) is a protein produced by cells in the prostate gland and released into the bloodstream. PSA levels are measured using a blood test. Although there is no such thing as a "normal PSA" for anyone at any given age, a higher-than-normal level of PSA can be found in people with prostate cancer. Prostate-specific antigen (PSA) blood test. PSA is a protein made in the prostate. PSA levels go up when the prostate becomes enlarged. But higher PSA levels also can be due to recent procedures, illnesses, surgery or prostate cancer. Sign up for free and stay up to date on research advancements, health tips, current health topics, and The most accurate predictor of prostate cancer on biopsy was percent free PSA (0.68) versus age (0.50), total PSA (0.57), or rectal examination findings (0.58). Of patients with percent free PSA below 14%, 59% had prostate cancer. Screening for prostate cancer begins with a test that measures the amount of prostate-specific antigen (PSA) protein in the blood. An elevated PSA level may be caused by prostate cancer but can also be caused by other conditions, including an enlarged prostate (benign prostatic hyperplasia) and inflammation of the prostate (prostatitis The prostate-specific antigen (PSA) test is a screening test for prostate cancer, as well as a method for monitoring the treatment of the disease and testing for recurrence.Like other early detection cancer screening tests, it is designed to alert a person to the presence of disease before any symptoms occur. At the current time, most prostate cancers are detected in this way, via this blood For doctor- or location- specific contact information, search UPMC Hillman Cancer Center doctors and locations. For the Mario Lemieux Center for Blood Cancers, call 412-864-6600. Learn more about prostate-specific antigen (PSA) blood testing, and find out how larger amounts of PSA are released when the gland is enlarged or infected. For men < 50 or those at high risk of prostate cancer, a lower cutoff (PSA > 2.5 ng/mL [2.5 mcg/L]) may be used. Other measures, including rate of PSA increase, free-to-bound PSA ratio, and other markers, may be useful. (A full discussion of prostate cancer screening and diagnosis Diagnosis Prostate cancer is usually adenocarcinoma. Symptoms If your PSA test result is in the borderline range (between 4 and 10), the percent-free PSA might be used to help decide if you should have a prostate biopsy. A lower percent-free PSA means that your chance of having prostate cancer is higher and you should probably have a biopsy. The PSA Prostate Cancer Screening Test from Labcorp uses a blood sample to measure the level of prostate-specific antigen (PSA) in your blood. High levels of PSA can be an indicator of prostate cancer and other prostate conditions, so this test may help with early diagnosis and treatment. The free total PSA ratio is created to differentiate between chronic prostatitis and prostate cancer for those who have PSA above 4 ng/mL and below 10 ng/mL to avoid unnecessary prostate biopsies. So you should not worry about it. After the age of 50 prostate starts to enlarge, and it can cause symptoms. eGFlJ19.